Successful Treatment of Acute Aluminum Phosphide Poisoning: Possible Benefit of Olive Oil - A Case Report
DOI:
https://doi.org/10.52547/uiemj.1.1.47Keywords:
Aluminum phosphide, Phosphine, Olive Oil, Gastric lavage, Emergency departmentAbstract
Aluminum phosphide (ALP) is a highly efficient pesticide that is widely applied in agriculture, but it is also one of the most commonly used suicide poisons. The management of ALP poisoning is limited to primarily supportive care in the absence of a particular antidote. Treatment options include gastric lavage with different solutions as well as the potassium permanganate, activated charcoal and sorbitol, coconut or almond oil, administration of N-acetyl cysteine, Magnesium sulfate, and methylene blue supplementation. While still there is no reliable protocol available and ALP poisoning is associated with a high mortality rate. Here we report a new method of gastric decontamination with olive oil and supportive medical therapy with vitamin E, N-acetyl cysteine, and magnesium sulfate. A 33-year-old man was admitted to the Emergency Department because of the intentional ingestion of three ALP tablets. The patient had decreased consciousness, sweating, paleness, and weak peripheral pulses. On bedside echocardiography, ejection fraction (EF) was 30%, showing cardiac toxicity of ALP. The patient was also suffering from metabolic acidosis (pH=7.37). Gastric decontamination was started with Olive Oil in Emergency department and medical therapy with vitamin E, N-acetyl cysteine, and magnesium sulfate was performed. During the hospitalization period, EF and metabolic acidosis were improved and the patient was discharged 8 days later.
Consent For Publication:
Patient consent to publication of study if his personal data stays confidential.
Availability of Data and Materials:
All data are available in article.
Competing interests:
None.
Funding:
None.
Authors' contributions:
MHK, PZ, MF, and SH contributed to the management of the patient. AT, MHK, and PZ have written the draft manuscript. All authors confirmed the final manuscript.
Acknowledgments:
None.
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